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New NIH Program Funds Efforts to Improve Gender Equality in Science, Health Care

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A new program from the Office of Research on Women’s Health (ORWH) at the National Institutes of Health (NIH) aims to improve gender and gender-specific training in science, medicine, and other health care professions. increase. Address the intentional integration of sexual and gender considerations into NIH research. Specifically, as breakthroughs in women’s health research continue to occur at every stage of biomedical research, the paradigm shift from women’s inclusion to gender- and gender-related differences and deliberate integration of information involves , requires the development of new skills and innovative methodologies. .

The program, called Promoting Health Equity Through Novel and Diverse Educational Resources (GENDER)R25, funds courses and curricula for health professionals at all career stages to ensure that health is a biological variable. Helps address issues related to gender and/or how it is affected by gender. Gender as an identity, social, cultural, or structural variable. NIH officials will also host a technical assistance webinar on Wednesday, September 21, for all medical professionals interested in learning more. Funded projects will lead to the development of cross-disciplinary curricula, courses and methods, which will be made available through the ORWH E-Learning web page.

Specifically, Dr. Elizabeth Barr, Director of Social and Behavioral Scientists at ORWH, explained further in the following interview: Pharmacy Times ORWH welcomes applications from pharmacy professionals and the rest of the biomedical community as pharmacists are critical members of the patient healthcare team and have a direct impact on the management of side effects (AEs), dosage and polypharmacy To do. All of these can affect women more than men. This is due to the limited nature of the data on these subjects in relation to gender and gender-related differences.

“Despite concerted efforts, sex and gender remain under-examined in curricula within biomedical education programs, including pharmacy programs,” Barr said. With its own discipline-specific language and accreditation standards, pharmacy professionals are ideally placed to develop curricula to fill gaps within their discipline.Pharmacy professionals applying for GENDER R25 I look forward to your consideration.”

Recognizing the distinct effects of sex and gender on health, the use of explicit terms for gender and gender will facilitate more accurate research into human health and the provision of health care by professionals in the field. essential to promote. A multidimensional structure based on clusters of anatomical and physiological traits, the gender taxonomy includes external genitalia, secondary sex characteristics, gonads, chromosomes, and hormones. However, gender is often misunderstood as an extension or synonym of sex. Instead, gender is a social and cultural variable that encompasses a range of domains, including gender identity and expression, gender roles and norms, gender relations, structural sexism, power, and equity.

“Understanding the impact of gender on health will facilitate the provision of equitable care by all biomedical professionals,” Barr said. “All pharmacy professionals can benefit from a better understanding of the sexual and gender space. [in their practices]”

By understanding the differences in terminology and the impact of both sex and gender on patient health, pharmacy professionals can better deliver more effective, personalized and patient-centred services. increase. For example, at the individual level, a health professional herself can influence the outcome of a patient’s care based on the results of her one-on-one communication with the patient regarding the patient’s symptoms.

In addition, gender can affect patient health at the relational and structural levels as well. At the relationship level, gender may influence whether a patient experiences intimate partner violence in the home setting, whereas the structural effects of gender may include specific female-specific geographic Based on location, different levels of access to healthcare may be included. conditions.

Federal law and NIH policy mandate the inclusion of women, minorities, and individuals throughout their lives in NIH-funded clinical research. Importantly, however, this not only involves enrolling women in the study, but the study design also needs to be considered. should be designed to When women are included but gender-specific results are not collected and reported, women and health professionals lack important knowledge that can affect patient health.

In addition, gender differences can also affect therapeutic outcomes, such as through altered levels of drug absorption, metabolism, and excretion. For example, women typically have different amounts of adipose tissue, different hormonal milieu, and may have different renal and hepatic function compared to men, all of which can affect dosage and AEs. There is a nature. Despite these known effects, women are often underrepresented in clinical trials, and potential drug distribution differences remain unidentified, which may prevent results from being disaggregated by gender.

Gender may also influence whether and how patients report adverse events and how their effects are perceived by health professionals. Women frequently report experiencing their reported symptoms being dismissed in medical settings, and this experience has been confirmed by studies published in journals. This can lead to delayed dose adjustments, accumulation of adverse events, and even discontinuation of effective therapy.

Sex and gender issues remain unexplored in biomedical education programs, including pharmacy schools. Working with multiple specialists and health care professionals in the patient care team enables pharmacists to improve the discussion of gender and gender differences and the use of appropriate terminology for patients by bridging gaps during communication with these professionals. GENDER R25 is perfectly positioned to help pharmacists in these efforts by improving education on these issues in pharmacy programs, You can spread it to other fields and make use of it.

For pharmacists interested in learning more, a technical assistance webinar on Wednesday, September 21 will give potential applicants the opportunity to learn about the scope, objectives, and requirements of the GENDER R25 program. ORWH staff, participating her NIH institutes and centers, and members of the NIH Center for Scientific Review also participate in the discussion to provide details of the program and answer applicants’ questions. Those interested in applying for funding should submit their non-AIDS applications by 5:00 PM EDT on October 27, 2022 and June 27, 2023, and HIV/AIDS applications by January 2023. Deadlines on the 7th and September 7th. 2023.

“Sector-specific training on sex and gender, such as that supported through Gender R25, provides opportunities for pharmaceutical professionals to advance pharmaceutical education, research and practice, thereby improving human health.” said Barr. “The benefits of improved participation in clinical research and enhanced gender and gender integration in all aspects of pharmacy research and care are impressive and achievable.”

Additionally, ORWH offers other resources and programs for career development and interprofessional education, including:

Developed in collaboration with the FDA’s Office of Women’s Health, this course explores gender and gender-related differences in key disease areas. The six modules included provide biomedical researchers, clinicians, and students of the medical profession with knowledge they can use to design and conduct research and/or interpret evidence for clinical practice.

Developed with funding from the National Institute of General Medical Sciences, this course helps researchers understand and apply the NIH Policy on Sex as a Biological Variable (SABV) in study design, analysis, and reporting. help you to His four modules of the course address basic, preclinical, clinical, and population health research.

The six-module course is designed to help the biomedical research community explain and appropriately teach SABV policy.

Individuals or teams can use the self-paced induction training, downloadable slide decks, and accompanying facilitator guides for researchers, clinicians, and policy makers to demonstrate how gender can be beneficially incorporated. You can start a dialogue about why. – A gender lens into research and clinical care.

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